Intra-articular hyaluronic acid compared to intra-articular triamcinolone hexacetonide in inflammatory knee osteoarthritis

Therapeutic Efficacy of Intra-Articular Hyaluronic Acid in Osteoarthritis Knee

Osteoarthritis (OA) is an increasingly important public health problem [1]. It is slowly progressive, can cause symptoms ranging from mild to disabiling. Osteoarthritis is a common cause of knee pain especially in the elderly. It is characterised by loss of articular cartilage, subchondral sclerosis, joint deterioration and osteophyte formation [1]. The current treatment for knee OA consists of...

Intra-articular hyaluronic acid injections for knee osteoarthritis.

Knee osteoarthritis is a common but often difficult problem to manage in primary care. Traditional nonsurgical management, consisting of lifestyle modification, physical therapy and pharmacologic therapy (e.g., analgesics, anti-inflammatory medications), is often ineffective or leaves residual symptoms. Viscosupplementation is a newly available option for patients with symptomatic knee osteoart...

Updates on intra-articular hyaluronic Acid therapy for knee osteoarthritis.

Intra-articular triamcinolone hexacetonide in knee osteoarthritis: factors influencing the clinical response.

OBJECTIVE To assess the efficacy of a single intra-articular injection of triamcinolone hexacetonide (THA) in knee osteoarthritis (OA) and examine factors which may relate to treatment efficacy. METHODS Eighty four patients with clinical and radiographic evidence of knee OA were recruited and randomly allocated to receive either THA (20 mg in 1 ml) or placebo (0.9% normal saline, 1 ml). Follo...

Intra-articular corticosteroid for knee osteoarthritis.

BACKGROUND Knee osteoarthritis is a leading cause of chronic pain, disability, and decreased quality of life. Despite the long-standing use of intra-articular corticosteroids, there is an ongoing debate about their benefits and safety. This is an update of a Cochrane review first published in 2005. OBJECTIVES To determine the benefits and harms of intra-articular corticosteroids compared with...